Accurate Structure Prediction of CDR H3 Loops Enabled by a Novel Structure-Based C-Terminal Constraint
نویسندگان
چکیده
منابع مشابه
Antibody H3 Structure Prediction
Antibodies are proteins of the immune system that are able to bind to a huge variety of different substances, making them attractive candidates for therapeutic applications. Antibody structures have the potential to be useful during drug development, allowing the implementation of rational design procedures. The most challenging part of the antibody structure to experimentally determine or mode...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2016
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1601137